Alnix Syrup/Alnix Drops

Cetirizine dihydrochloride.

Each 5 mL (1 teaspoonful) syrup contains: Cetirizine dihydrochloride 5 mg.
Each mL syrup (oral drops) contains: Cetirizine dihydrochloride 2.5 mg.
TasteRite Technology is a unique tastemasking system developed specifically for liquid dosage forms. This technology significantly reduces the bitterness of medicine so that children taste the flavor and not the medicine.

These medicines contain cetirizine, an anti-allergy. Cetirizine blocks the action of histamine, a substance that causes allergic symptoms. Cetirizine is less likely to cause drowsiness and dizziness than the older class of anti-allergy medicines.

These medicines are used for the relief of symptoms associated with: allergic rhinitis such as sneezing; runny, itchy nose; and itchy, watery eyes; allergic conjunctivitis; skin symptoms of allergy such as itch and rash.

The medicine should be taken orally (by mouth). (See table.)

Click on icon to see table/diagram/image

Missed Dose: Take the missed dose as soon as remembered then the subsequent dose as recommended, i.e., after 24 hours (if once daily) or after 12 hours (if twice daily).
Do not double the dose.

Signs and symptoms of cetirizine overdose include sleepiness, drowsiness, restlessness, and irritability.
If the patient has taken more than the recommended dosage, consult a doctor.

If the patient is allergic to cetirizine or other ingredients in the product.

May cause drowsiness. Exercise caution when engaging in activities requiring mental alertness.
Consult a doctor: Before taking this medication, tell the doctor if the patient has kidney or liver disease. The patient may need dosage adjustment or special monitoring during treatment.

The following undesirable effects have been reported: In adults and children 12 years and older: Drowsiness/sleepiness; Excessive tiredness; Dry mouth; Sore throat; Dizziness; Headache; Nausea.
In children 6 to 11 years old: Headache; Sore throat; Stomach pain; Coughing; Drowsiness/Sleepiness; Diarrhea; Bronchospasm (sudden, uncontrolled narrowing of airways in lungs); Epistaxis (nose bleeding); Nausea; Vomiting.
The following rare events have been reported but it is not known whether they are directly related to cetirizine use.
Nervous System: Ataxia (uncontrolled muscle movement, incoordination), confusion, abnormal thinking, agitation, amnesia, anxiety, convulsions, depersonalization (alteration in the perception of the self so that the usual sense of one's own reality is lost), depression, dysphonia (difficulty in speaking), emotional lability (emotional instability), euphoria (an exaggerated unrealistic sense of well-being), impaired concentration, insomnia/sleep disorders, nervousness, hyperesthesia (increased sensitivity to any stimulation), hypoesthesia (abnormally decreased sensitivity), hyperkinesia (hyperactivity), hypertonia (muscle stiffness), migraine, myelitis (inflammation of the spinal cord), paralysis, paresthesia (abnormal sensation, such as burning, prickling, or tingling), ptosis (drooping of eyelids), syncope (fainting/temporary loss of consciousness), tremor, twitching, vertigo.
Cardiovascular: Palpitation, tachycardia (rapid heart rate), increased blood pressure, chest pain, heart failure, rarely decreased blood pressure.
Respiratory: Bronchitis, dyspnea (shortness of breath), hyperventilation (rapid breathing), increased sputum, pneumonia, respiratory disorder, rhinitis, sinusitis, upper respiratory tract infection.
Gastrointestinal: Anorexia (loss of appetite), increased appetite, increased salivation, tongue discoloration, swelling of tongue, tooth caries, taste loss, taste perversion, dyspepsia, gastritis, stomatitis/ulcerative stomatitis (sores in the mouth), enlarged abdomen, eructation (burping), flatulence (gassiness), constipation, melena (black stools caused by bleeding in the stomach or small intestine), rectal bleeding, hemorrhoids.
Genitourinary and Renal: Cystitis (inflammation of the urinary bladder), dysuria (painful urination), hematuria (blood in the urine), polyuria (excessive urination/frequent urination), urinary incontinence (inability to control urination), urinary retention (difficulty urinating), urinary tract infection, glomerulonephritis (inflammation of the kidney).
Reproductive: Dysmenorrhea, intermenstrual bleeding (bleeding between two menstrual periods), female breast pain, leucorrhea (whitish vaginal discharge), menorrhagia (heavy menstrual bleeding), decreased libido, vaginitis (inflammation of the vagina).
Hepatic: Hepatitis and increased liver enzymes (e.g, aminotransferases, bilirubin).
Ocular (Eye) and Otic (Ear): Visual problems, blindness, conjunctivitis (irritation and redness of the thin membrane covering the eye), eye pain, glaucoma, loss of eye accommodation, eye bleeding, periorbital edema (accumulation of fluid surrounding the socket of the eye), xerophthalmia (dry eye), deafness, otalgia (earache), ototoxicity (toxicity to the ears), tinnitus (ringing in the ears).
Skin: Acne, alopecia (baldness), angioedema (rapid swelling of the skin), bullous eruption (large blisters), dermatitis (skin inflammation), dry skin, eczema, furunculosis (boils), hyperkeratosis (thickened skin), hypertrichosis (excessive hair growth), increased sweating, light sensitivity, pruritus (itchiness), purpura (small purple-red marks in skin), urticaria/rash, seborrhea, skin disorder, skin nodule.
Musculoskeletal: Arthralgia (joint pain), arthritis, arthrosis/osteoporosis, muscle weakness, myalgia (muscle aches), asthenia (weakness), malaise (feeling of bodily discomfort), leg cramps.
Other undesirable effects: Anaphylaxis (rare, life-threatening allergic reaction), back pain, cholestasis (inflammation of the gall bladder), dehydration, diabetes mellitus, swelling (generalized, facial, leg, or peripheral), fever, increased weight, lymphadenopathy (swelling of the lymph nodes), pallor, rigors (shaking), hemolytic anemia (anemia resulting from destruction of red blood cells), thrombocytopenia (decreased number of platelets), parosmia (distorted sense of smell), thirst.

Do not use this product together with alcohol, medicines for anxiety or sleep disorder (e.g., Alprazolam, Diazepam, Chlordiazepoxide, Temazepam, Triazolam, etc.), medicines for depression (e.g., Amitriptyline, Doxepin, Nortriptyline, Fluoxetine, Sertraline, Paroxetine, etc.), other cold or allergy medicines, or any other medicines that cause drowsiness, sleepiness, and relaxation because of the possibility for increased toxicity.

Store at temperatures not exceeding 30°C.

Antihistamines & Antiallergics

R06AE07 - cetirizine ; Belongs to the class of piperazine derivatives used as systemic antihistamines.

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